Spinach Chicken Casserole with Cream Cheese and Mozzarella – All of the delicious flavors of cream cheese, spinach, and chicken are packed into this delicious dinner recipe! This easy spinach chicken breasts casserole recipe comes together quickly and makes a nice combination for a busy meal. As a bonus, this chicken casserole recipe is also keto diet-friendly, gluten-free, and low-carb. Enjoy!
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Ingredients List For The Spinach Chicken Casserole Recipe
- 2 large boneless skinless chicken breasts, cut horizontally
- 8 oz cream cheese, softened
- 2 cups spinach, rinsed
- 2 tablespoons olive oil, divided
- 4 oz Mozzarella cheese, shredded
- 3 cloves garlic, minced
- 1/2 teaspoon red pepper flakes, optional
- 1/2 teaspoon salt
- 1/2 teaspoon pepper
- 1/2 teaspoon Italian seasoning, optional
Photo credit: © Eatwell101.com
Chicken casserole recipe
This spinach chicken casserole with cream cheese and mozzarella is super simple to make and so comforting! With simple ingredients like chicken breasts, spinach, garlic, cream cheese, mozzarella cheese, spices, and seasoning, you’ll have yourself this delicious creamy chicken casserole in less than 40 minutes of preparation. In our opinion, this casserole isn’t complete without the bubbly mozzarella topping. It’s the perfect chicken dinner casserole for busy weeknights!
Key Ingredients for the chicken casserole
- Chicken breasts: fresh or thawed. If too thick, you can slice them horizontally to make cutlets; this way, they will cook faster, and you won’t get pink, undercooked chicken.
- Cream cheese: This is the heart and spirit of this casserole. Cream cheese brings chunkiness and binds all the flavors together.
- Spinach: Fresh spinach, not canned ;)
- Olive oil
- Mozzarella: You can also try a cheese blend like Mozzarella/Provolone/Parmesan.
- Fresh garlic
- Red pepper flakes, optional
- Salt and pepper
- Italian seasoning, optional
How to make chicken casserole
The method for this chicken casserole is very easy and requires only a few steps.
Photo credit: © Eatwell101.com
Arrange the marinated chicken breasts into a baking dish. Add more seasoning if you like. Note that we cut our chicken breast pretty thin to make cutlets, so the chicken cooks quickly.
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Spread cream cheese on top of the chicken breast. It’s easier when the cream cheese is at room temperature.
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Top the cream cheese with sauteed spinach. We sauté the spinach first, so it renders some of its water and doesn’t make the chicken casserole soggy when baking.
Photo credit: © Eatwell101.com
Sprinkle the chicken casserole with shredded mozzarella cheese before popping in the oven at 400ºF (200ºC).
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Directions
1. To prepare the spinach chicken casserole: Add olive oil, garlic, Italian seasoning, and red pepper flakes into a Ziplock bag along with 1/2 teaspoon of salt and 1/2 teaspoon of black pepper. Seal the bag and shake until mixed. Add the chicken breasts, seal, and massage so the chicken breasts are covered in the marinade. Set aside for 10-15 minutes on the counter while you prep the remaining ingredients. Position a rack in the center of the oven and preheat the oven to 400ºF (200°C).
2. Quickly wilt the spinach in a skillet with 1 tablespoon olive oil and set aside.
3. Arrange chicken breasts drained from the marinade in a baking dish. Spread the softened cream cheese over the chicken breasts and lay spinach on top of the cream cheese. Finally, sprinkle mozzarella over the top.
4. Bake the spinach chicken casserole for 20-30 minutes. Chicken casserole is done when cooked to an internal temperature of 165˚F (75°C). Serve the spinach chicken casserole warm with a side of cauliflower rice or baked veggies. Enjoy!
Photo credit: © Eatwell101.com
Tips for the Spinach Chicken Breasts Casserole Recipe
- You can cut the chicken breasts into cubes to help the marinade coat the chicken more deeply and speed up the baking time of the casserole.
- Freeze individual portions of the spinach chicken breasts casserole, so you have a comforting dinner for evenings when you don’t feel like cooking from scratch. See the instructions below for reheating frozen chicken casserole.
- Cream cheese and mozzarella should provide enough salt, so go easy with the salt in the marinade.
- If you like your chicken casserole spicier, add a teaspoon of Cayenne into the marinade, or combine one-half the spices with the cream cheese before spreading on top of the chicken and spinach.
What to serve with the creamy chicken casserole
You can serve this best chicken casserole with some green beans, roasted asparagus, cauliflower rice, or broccoli on the side.
Can we freeze the chicken casserole?
Absolutely! This easy chicken casserole with spinach makes an amazing make-ahead meal or freezer meal. You can freeze the casserole baked or unbaked:
- To bake the uncooked chicken casserole after freezing, thaw the chicken casserole overnight in the refrigerator and bake as directed in the instructions. We do not recommend baking the chicken casserole straight out of the freezer because it would take a very long time and not cook evenly.
- To reheat the baked casserole after freezing: same method, thaw overnight in the refrigerator; then cover the chicken casserole with foil and bake at 350ºF (180ºC) for 20-30 minutes or until heated through.
What do other readers say about this chicken breast casserole recipe
“One of my new favorite ways to eat chicken. Have made quite a few times recently. It’s so good and easy!” – Brittani
“Phenomenal!!! I omitted the red pepper bc I don’t like spicy but otherwise, it was amazing!!!” – Stephanie
“Very good and pretty quick and easy to make. My husband said it might be his favorite chicken dish, and he does not like chicken. I will definitely make this again and will probably sauté some mushrooms with the spinach.” – Tiffany
“Soooo good, and sooo easy. I just mixed a small jar of pesto with a block of softened cream cheese, then mixed in some torn fresh spinach. Smother the salt and peppered chicken breasts then sprinkle with shredded mozzarella. 375 for 40mins (they were fat breasts). Yum!” – Mel
More chicken casserole recipes
- Fajita Chicken Casserole
- French Onion Chicken Casserole
- Jalapeño Popper Chicken Casserole
- Broccoli Chicken Casserole with Cream Cheese and Mozzarella
Photo credit: © Eatwell101.com
Spinach Chicken Casserole with Cream Cheese and Mozzarella
Chicken breasts casserole recipe is packed with delicious flavors - Try the chicken casserole with spinach, cream cheese, and mozzarella for a nice combination for a busy day's meal!
- 2 large boneless skinless chicken breasts, cut horizontally
- 8 oz cream cheese, softened
- 2 cup spinach, rinsed
- 2 tablespoons olive oil, divided
- 4 oz Mozzarella cheese, shredded
- 3 cloves garlic, minced
- 1/2 teaspoon red pepper flakes, optional
- 1/2 teaspoon salt
- 1/2 teaspoon pepper
- 1/2 teaspoon Italian seasoning, optional
Instructions
- Add olive oil, garlic, Italian seasoning, and red pepper flakes into a Ziplock bag along with 1/2 teaspoon of salt and 1/2 teaspoon black pepper. Seal the bag and shake until mixed.
- Add the chicken breasts, seal, and massage so the chicken breasts are covered in the marinade, set aside for 10-15 minutes on the counter while you prep the remaining ingredients.
- Position a rack in the center of the oven and preheat the oven to 400ºF (200°C).
- Quickly wilt the spinach in a skillet with 1 tablespoon olive oil and set aside.
- Arrange chicken breasts drained from the marinade in a baking dish. Spread the softened cream cheese over the chicken breasts and lay spinach on top of the cream cheese. Finally, sprinkle mozzarella over the top.
- Bake the spinach chicken casserole for 20-30 minutes. Chicken casserole is done when cooked to an internal temperature of 165˚F (75°C).
- Serve the spinach chicken casserole warm with a side of cauliflower rice or baked veggies. Enjoy!
Recipe Notes
- Cream cheese and mozzarella should provide enough salt, so go easy with the salt in the marinade.
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Reviews (79)
Leave a reviewLeave a Reply
Lisia
2026-02-22 20:17:33
I made this for my family and they loved it. Will make again
Becca
2024-09-22 17:55:22
I made this last night and it was fantastic! I used an herbed cream cheese (only 1-1.5Tb per breast, which was *plenty*). I also doubled the spinach!
Lauren
2024-05-12 10:16:25
Great recipe with minimal ingredients. I used 3 pieces of chicken (cut lengthwise) and a whole bag of spinach. The only thing I would say is it didn’t need that much cream cheese. Way too much was the vote from my family. I will be making this again, for sure, but will adjust the cream cheese.
Gail High
2024-03-24 18:02:56
I’ve made this twice. It’s great but I do have one suggestion. By seasoning the cream cheese before spreading it on the chicken was an improvement.
Shawn
2024-01-09 18:24:34
Excellent and so simple. The marinade is fantastic.
